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  1. We present an efficient and scalable partitioning method for mapping large-scale neural network models with locally dense and globally sparse connectivity onto reconfigurable neuromorphic hardware. Scalability in computational efficiency, i.e., amount of time spent in actual computation, remains a huge challenge in very large networks. Most partitioning algorithms also struggle to address the scalability in network workloads in finding a globally optimal partition and efficiently mapping onto hardware. As communication is regarded as the most energy and time-consuming part of such distributed processing, the partitioning framework is optimized for compute-balanced, memory-efficient parallel processing targeting low-latency execution and dense synaptic storage, with minimal routing across various compute cores. We demonstrate highly scalable and efficient partitioning for connectivity-aware and hierarchical address-event routing resource-optimized mapping, significantly reducing the total communication volume recursively when compared to random balanced assignment. We showcase our results working on synthetic networks with varying degrees of sparsity factor and fan-out, small-world networks, feed-forward networks, and a hemibrain connectome reconstruction of the fruit-fly brain. The combination of our method and practical results suggest a promising path toward extending to very large-scale networks and scalable hardware-aware partitioning. 
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  2. Real-time spike sorting with large data throughput is essential for studying neural dynamics and brain-machine interfaces. Neural recordings from high-density multi-electrode arrays that consist of hundreds of electrodes impose stringent demands on spike sorting hardware regarding data transmission bandwidth and computation complexity. That leads to an urgent need for specialized hardware with high throughput, low power, and latency. Here, we present a real-time spike sorting processor that utilizes high-density BEOL-integrable CuO x resistive crossbars to perform in-memory spike segregation. We experimentally demonstrate, for the first time, efficient hardware implementation of spike sorting from in vivo extracellular recordings with high accuracy. Our neuromorphic interface promises substantial performance gains ( ∼1000×less area,∼200×less power,4.8 μs latency for sorting 100 channels) for in vivo real-time spike sorting. 
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